DIGITAL ELLIPTICAL PRODUCT LABA-19
STRUCTURAL BIOCHEMISTRY & DOCKING STUDIO

BioGen Molecule Designer Studio

Manipulate 3D ribbon backbones, model point mutations across binding interfaces, and optimize thermodynamic stability.

Candidate Variants2 DESIGNS
VAR-9801AFFINITY_OPTIMIZED

BG-NeoClamp-481

KRAS0.42 nM Kd
VAR-9802WET_LAB_DISPATCHED

BG-mAb-IL17-HyperBinder

Interleukin-17A0.18 nM Kd
BG-NeoClamp-481Target: KRAS G12D Oncogenic Switch Complex · Docking: 98.4%
BINDING AFFINITY (KD)0.42 nM Sub-Nanomolar
FREE ENERGY (ΔG)-14.8 kcal/mol
STRUCTURAL CONFORMATIONAL POCKET

Conforms to target allosteric pocket with 0.8 Å C-alpha RMSD alignment.

Melting Temp Tm: 78.4 °CToxicity: MINIMAL
ENGINEERED BY DIGITAL ELLIPTICAL

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